Megan Stanifer


List of Publications

USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING.

A model for network-based identification and pharmacological targeting of aberrant, replication-permissive transcriptional programs induced by viral infection

Genetic regulation of OAS1 nonsense-mediated decay underlies association with COVID-19 hospitalization in patients of European and African ancestries

A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells

The FDA-Approved Drug Cobicistat Synergizes with Remdesivir To Inhibit SARS-CoV-2 Replication In Vitro and Decreases Viral Titers and Disease Progression in Syrian Hamsters

The link between menin and pleiotrophin in the tumor biology of pancreatic neuroendocrine neoplasms

Conserved Induction of Distinct Antiviral Signalling Kinetics by Primate Interferon Lambda 4 Proteins

Invasiveness of Escherichia coli Is Associated with an IncFII Plasmid

Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5

Adapting Gastrointestinal Organoids for Pathogen Infection and Single Cell Sequencing under Biosafety Level 3 (BSL-3) Conditions

Single-cell transcriptomics reveals immune response of intestinal cell types to viral infection

TMPRSS2 expression dictates the entry route used by SARS-CoV-2 to infect host cells

The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity

Selective Janus kinase inhibition preserves interferon-λ-mediated antiviral responses

Single-cell analyses reveal SARS-CoV-2 interference with intrinsic immune response in the human gut

Microscopy-based assay for semi-quantitative detection of SARS-CoV-2 specific antibodies in human sera: A semi-quantitative, high throughput, microscopy-based assay expands existing approaches to measure SARS-CoV-2 specific antibody levels in human sera

SARS-CoV-2 infection remodels the host protein thermal stability landscape

Importance of Type I and III Interferons at Respiratory and Intestinal Barrier Surfaces

Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor.

SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography.

The origin of diarrhea in rotavirus infection.

A colorimetric RT-LAMP assay and LAMP-sequencing for detecting SARS-CoV-2 RNA in clinical samples

Critical Role of Type III Interferon in Controlling SARS-CoV-2 Infection in Human Intestinal Epithelial Cells

3D Correlative Cryo-Structured Illumination Fluorescence and Soft X-ray Microscopy Elucidates Reovirus Intracellular Release Pathway

NSs amyloid formation is associated with the virulence of Rift Valley fever virus in mice

Novel Toscana Virus Reverse Genetics System Establishes NSs as an Antagonist of Type I Interferon Responses

Enhanced Uptake and Endosomal Release of LbL Microcarriers Functionalized with Reversible Fusion Proteins

Asymmetric distribution of TLR3 leads to a polarized immune response in human intestinal epithelial cells

Type-Specific Crosstalk Modulates Interferon Signaling in Intestinal Epithelial Cells

Teratogenic Rubella Virus Alters the Endodermal Differentiation Capacity of Human Induced Pluripotent Stem Cells

Hypoxic Environment Promotes Barrier Formation in Human Intestinal Epithelial Cells through Regulation of MicroRNA 320a Expression

Differential Regulation of Type I and Type III Interferon Signaling

Novel Chimeric Gene Therapy Vectors Based on Adeno-Associated Virus and Four Different Mammalian Bocaviruses

Differential induction of interferon stimulated genes between type I and type III interferons is independent of interferon receptor abundance

Rubella Virus Strain-Associated Differences in the Induction of Oxidative Stress Are Independent of Their Interferon Activation

Reversible Fusion Proteins as a Tool to Enhance Uptake of Virus-Functionalized LbL Microcarriers

Genome packaging of reovirus is mediated by the scaffolding property of the microtubule network

Reovirus inhibits interferon production by sequestering IRF3 into viral factories

Type I and Type III Interferons Display Different Dependency on Mitogen-Activated Protein Kinases to Mount an Antiviral State in the Human Gut